New colon cancer drugs to be developed from newly discovered protein.
Some scientists recently discovered new mechanisms by which a protein prevents colon cancer.
Researchers discovered that a protein known as APC cause a mouth watering drop on a couple of pathways that cause the development of colon cancer.
Dr. Yashi Ahmed and colleagues recently reported their results in the journal
Developmental Cell.
Colorectal cancer: Which begins in the colon or the rectum is currently the most common cancer in the United States. It is also the third leading cause of cancer-related death.
As calculated by previous observations, around 97,220 new cases of colon cancer are expected to be diagnosed in the U.S this year!!
Scientists have already pinpointed APC which is a protein endowed by the APC gene as a very possible target for the prevention of colorectal cancer.
The protein controls the growth and division of cells, causing them to stop going out of control and creating tumors.
Role of APC ‘broader and multifaceted’
Dr. Ahmed and colleagues explain further that when it comes to the cancer-protecting role of APC, it was believed that the protein aims and destroys a single “activator” specifically, a protein called beta-catenin to prevent colon cancer.
By studying the APC deficient cells of fruit flies which harbor about 75 percent of the genes that cause human disease the scientist discovered other mechanisms by which APC can halt colon cancer.
In extreme circumstances, the doctors there can determine if surgery is needed to tighten the muscles between the esophagus and stomach so that acid cannot flow upward. Atlanta Endoscopy Center